4CXX: Crystal structure of human FTO in complex with acylhydrazine inhibitor 16

PDB ID: 4CXXDownload
MMDB ID: 123524
PDB Deposition Date: 2014/4/9
Updated in MMDB: 2014/10
Experimental Method:
x-ray diffraction
Resolution: 2.76  Å
Source Organism:
Similar Structures:
Biological Unit for 4CXX: monomeric; determined by author and by software (PISA)
Molecular Components in 4CXX
Label Count Molecule
Protein (1 molecule)
1
Alpha-ketoglutarate-dependent Dioxygenase FTO
(Gene symbol: FTO)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
NICKEL (II) IONNICKEL (II) ION
2
1
(2E)-4-{N'-[4-(4-tert-Butyl-benzyl)-pyridine-3-carbonyl]-hydrazino}-4-oxo-but-2-enoic acid(2E)-4-{N'-[4-(4-tert-Butyl-benzyl)-pyridine-3-carbonyl]-hydrazino}-4-oxo-but-2-enoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303