4CVA: Mps1 Kinase With 3-aminopyridin-2-one Inhibitors

PDB ID: 4CVADownload
MMDB ID: 128348
PDB Deposition Date: 2014/3/24
Updated in MMDB: 2015/04
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 4CVA: monomeric; determined by author and by software (PISA)
Molecular Components in 4CVA
Label Count Molecule
Protein (1 molecule)
1
Dual Specificity Protein Kinase TTK
(Gene symbol: TTK)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
N-(6-Oxo-1,6-Dihydro-3,4'-Bipyridin-5-Yl)-4-(Piperidin-1-Yl)benzamideN-(6-Oxo-1,6-Dihydro-3,4'-Bipyridin-5-Yl)-4-(Piperidin-1-Yl)benzamide
2
2
Dimethyl SulfoxideDimethyl Sulfoxide
3
2
1,2-Ethanediol1,2-Ethanediol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303