4CV8: MPS1 kinase with 3-aminopyridin-2-one inhibitors

PDB ID: 4CV8Download
MMDB ID: 128346
PDB Deposition Date: 2014/3/24
Updated in MMDB: 2019/05
Experimental Method:
x-ray diffraction
Resolution: 3  Å
Source Organism:
Similar Structures:
Biological Unit for 4CV8: monomeric; determined by author and by software (PISA)
Molecular Components in 4CV8
Label Count Molecule
Protein (1 molecule)
1
Dual Specificity Protein Kinase TTK
(Gene symbol: TTK)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
3-amino-5-(1-methyl-1H-pyrazol-4-yl)pyridin-2(1H)-one3-amino-5-(1-methyl-1H-pyrazol-4-yl)pyridin-2(1H)-one
2
4
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303