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4CRG:
Creating Novel F1 Inhibitors Through Fragment Based Lead Generation And Structure Aided Drug Design
PDB ID:
4CRG
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MMDB ID:
126821
PDB Deposition Date:
2014/2/26
Updated in MMDB:
2015/02
Experimental Method:
x-ray diffraction
Resolution:
1.25 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 4CRG: trimeric; determined by author and by software (PISA)
Molecular Components in 4CRG
Label
Count
Molecule
Proteins (3 molecules)
A
A_1
A_2
3
Coagulation Factor XI
(Gene symbol:
F11
)
Chemicals and Non-standard biopolymers (25 molecules)
1
12
Glycerol
2
3
6-Carbamimidoyl-N-Phenyl-4-(Pyrimidin-2-Ylamino)naphthalene-2-Carboxamide
3
10
Sulfate Ion
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303