NCBI
National Center for
Biotechnology Information
Search
4CPX:
Macrocyclic Transition-State Mimicking HIV-1 Protease Inhibitors Encompassing a Tertiary Alcohol
PDB ID:
4CPX
Download
MMDB ID:
125565
PDB Deposition Date:
2014/2/8
Updated in MMDB:
2014/12
Experimental Method:
x-ray diffraction
Resolution:
1.85 Å
Source Organism:
Human immunodeficiency virus
Similar Structures:
VAST+
Download sequence data
Biological Unit for 4CPX: dimeric; determined by author and by software (PISA)
Molecular Components in 4CPX
Label
Count
Molecule
Proteins (2 molecules)
A
B
2
Protease
Chemicals and Non-standard biopolymers (4 molecules)
1
3
CHLORIDE ION
2
1
methyl ~{N}-[(2~{S})-3,3-dimethyl-1-[2-[3-[(3~{R},6~{S},10~{Z})-3-oxidanyl-4,7-bis(oxidanylidene)-6-propan-2-yl-5,8-diazabicyclo[11.2.2]heptadeca-1(16),10,13(17),14-tetraen-3-yl]propyl]-2-[(4-thiophen-2-ylphenyl)methyl]hydrazinyl]-1-oxidanylidene-butan-2-yl]carbamate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303