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4CMB:
Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor and inhibitor
PDB ID:
4CMB
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MMDB ID:
126244
PDB Deposition Date:
2014/1/16
Updated in MMDB:
2023/12
Experimental Method:
x-ray diffraction
Resolution:
1.96 Å
Source Organism:
Trypanosoma brucei brucei
Similar Structures:
VAST+
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Biological Unit for 4CMB: tetrameric; determined by author and by software (PISA)
Molecular Components in 4CMB
Label
Count
Molecule
Proteins (4 molecules)
A
B
C
D
4
Pteridine Reductase 1
Chemicals and Non-standard biopolymers (9 molecules)
1
4
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
4
N4-cyclohexyl-5-(4-fluorophenyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
3
1
ACETATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303