4CJX: The Crystal Structure Of Trypanosoma Brucei N5, N10- Methylenetetrahydrofolate Dehydrogenase-cyclohydrolase (fold) Complexed With Nadp Cofactor And Inhibitor

PDB ID: 4CJXDownload
MMDB ID: 126602
PDB Deposition Date: 2013/12/23
Updated in MMDB: 2016/02
Experimental Method:
x-ray diffraction
Resolution: 2.05  Å
Source Organism:
Similar Structures:
Biological Unit for 4CJX: dimeric; determined by author and by software (PISA)
Molecular Components in 4CJX
Label Count Molecule
Proteins (2 molecules)
2
C-1-tetrahydrofolate Synthase, Cytoplasmic, Putative
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
GlycerolGlycerol
2
1
Di(Hydroxyethyl)etherDi(Hydroxyethyl)ether
3
2
(2s)-2-[[4-[[2,4-Bis(Azanyl)-6-Oxidanylidene-1h-Pyrimidin-5-Yl]carbamoylamino]phenyl]carbonylamino]pentanedioic Acid(2s)-2-[[4-[[2,4-Bis(Azanyl)-6-Oxidanylidene-1h-Pyrimidin-5-Yl]carbamoylamino]phenyl]carbonylamino]pentanedioic Acid
4
1
Nadp Nicotinamide-Adenine-Dinucleotide PhosphateNadp Nicotinamide-Adenine-Dinucleotide Phosphate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303