4BPE: The Crystal Structure Of The Eukaryotic 40s Ribosomal Subunit In Complex With Eif1 And Eif1a - Complex 1

Citation:
Abstract
Eukaryotic translation initiation factors (eIFs) 1A and 1 are central players in the complex process of start-codon recognition. To improve mechanistic understanding of this process, we determined the crystal structure of the 40S ribosomal subunit in complex with eIF1A and eIF1 from Tetrahymena thermophila at a resolution of 3.7 A. It reveals the positions of the two factors on the 40S and the conformational changes that accompany their binding.
MMDB ID: 111939
PDB Deposition Date: 2013/5/24
Updated in MMDB: 2013/11
Experimental Method:
x-ray diffraction
Resolution: 3.7  Å
Source Organism:
Similar Structures:
Merged PDB IDs:4BPE 4BPN 4BPO 4BPP
Asymmetric Unit for 4BPE: 144-meric
Molecular Components in 4BPE
Label Count Molecule
Proteins (140 molecules)
4
Translation Initiation Factor Eif-1a Family Protein
Molecule annotation
4
40S Ribosomal Protein Rps28e
Molecule annotation
4
40S Ribosomal Protein S8
Molecule annotation
4
40S Ribosomal Protein Rps7e
Molecule annotation
4
40S Ribosomal Protein S3A
Molecule annotation
4
40S Ribosomal Protein Rps26e
Molecule annotation
4
40S Ribosomal Protein S27
Molecule annotation
4
40S Ribosomal Protein Rps10e
Molecule annotation
4
40S Ribosomal Protein Rps25e
Molecule annotation
4
40S Ribosomal Protein Rps31e
Molecule annotation
4
40S Ribosomal Protein SA
Molecule annotation
4
40S Ribosomal Protein Rps3e
Molecule annotation
4
40S Ribosomal Protein Rps9e
Molecule annotation
4
40S Ribosomal Protein Rps2e
Molecule annotation
4
Eif1
Molecule annotation
4
40S Ribosomal Protein Rps5e
Molecule annotation
4
40S Ribosomal Protein Rps22e
Molecule annotation
4
40S Ribosomal Protein Rps16e
Molecule annotation
4
40S Ribosomal Protein Rps20e
Molecule annotation
4
40S Ribosomal Protein Rps14e
Molecule annotation
4
40S Ribosomal Protein S12
Molecule annotation
4
40S Ribosomal Protein Rps18e
Molecule annotation
4
40S Ribosomal Protein Rps29e
Molecule annotation
4
40S Ribosomal Protein Rps13e
Molecule annotation
4
40S Ribosomal Protein S24
Molecule annotation
4
40S Ribosomal Protein Rps11e
Molecule annotation
4
40S Ribosomal Protein Rack1
Molecule annotation
4
40S Ribosomal Protein Rps15e
Molecule annotation
4
40S Ribosomal Protein Rps19e
Molecule annotation
4
40S Ribosomal Protein Rps12e
Molecule annotation
4
40S Ribosomal Protein Rps17e
Molecule annotation
4
40S Ribosomal Protein Rps4e
Molecule annotation
4
40S Ribosomal Protein Rps30e
Molecule annotation
4
40S Ribosomal Protein S6
Molecule annotation
4
40S Ribosomal Protein Rps21e
Molecule annotation
Nucleotide(1 molecule)
4
18S rRNA
Molecule annotation
Chemicals (332 molecules)
1
16
2
316
* Click molecule labels to explore molecular sequence information.

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