4BIM: Catalase 3 From Neurospora Crassa In Tetragonal Form Exposes A Modified Tetrameric Organization

Polymorphism is frequently observed from different crystallization conditions. In proteins, the effect on conformational variability is poorly documented, with only a few reported examples. Here, three polymorphic crystal structures determined for a large-subunit catalase, CAT-3 from Neurospora crassa, are reported. Two of them belonged to new space groups, P1 and P43212, and a third structure belonged to the same space group, P212121, as the previously deposited 2.3 A resolution structure (PDB entry 3ej6), but had a higher resolution (1.95 A). Comparisons between these polymorphic structures highlight the conformational stability of tetrameric CAT-3 and reveal a distortion in the tetrameric structure that has not previously been described.
PDB ID: 4BIMDownload
MMDB ID: 109354
PDB Deposition Date: 2013/4/11
Updated in MMDB: 2013/07
Experimental Method:
x-ray diffraction
Resolution: 2.95  Å
Source Organism:
Similar Structures:
Biological Unit for 4BIM: tetrameric; determined by author and by software (PISA)
Molecular Components in 4BIM
Label Count Molecule
Proteins (4 molecules)
Catalase 3(Gene symbol: cat-3)
Molecule annotation
Chemicals (4 molecules)
* Click molecule labels to explore molecular sequence information.

Citing MMDB