4BCQ: Structure of CDK2 in complex with cyclin A and a 2-amino-4-heteroaryl- pyrimidine inhibitor

PDB ID: 4BCQDownload
MMDB ID: 254032
PDB Deposition Date: 2012/10/2
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Bos taurus▼
Similar Structures:
Biological Unit for 4BCQ: dimeric; determined by software (PISA)
Molecular Components in 4BCQ
Label Count Molecule
Proteins (2 molecules)
1
Cyclin-dependent Kinase 2
Molecule annotation
1
Cyclin-a2
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]-2-{[3-(morpholin-4-ylcarbonyl)phenyl]amino}pyrimidine-5-carbonitrile4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]-2-{[3-(morpholin-4-ylcarbonyl)phenyl]amino}pyrimidine-5-carbonitrile
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303