4BCO: Structure of CDK2 in complex with cyclin A and a 2-amino-4-heteroaryl- pyrimidine inhibitor

PDB ID: 4BCODownload
MMDB ID: 253843
PDB Deposition Date: 2012/10/2
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.05  Å
Source Organism:
Bos taurus▼
Similar Structures:
Biological Unit for 4BCO: dimeric; determined by software (PISA)
Molecular Components in 4BCO
Label Count Molecule
Proteins (2 molecules)
1
Cyclin-dependent Kinase 2
Molecule annotation
1
Cyclin-a2
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
2-[[3-(4-ethanoyl-1,4-diazepan-1-yl)phenyl]amino]-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidine-5-carbonitrile2-[[3-(4-ethanoyl-1,4-diazepan-1-yl)phenyl]amino]-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidine-5-carbonitrile
2
2
MONOTHIOGLYCEROLMONOTHIOGLYCEROL
3
2
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303