4BCK: Structure of CDK2 in complex with cyclin A and a 2-amino-4-heteroaryl- pyrimidine inhibitor

PDB ID: 4BCKDownload
MMDB ID: 255475
PDB Deposition Date: 2012/10/2
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.052  Å
Source Organism:
Similar Structures:
Biological Unit for 4BCK: dimeric; determined by software (PISA)
Molecular Components in 4BCK
Label Count Molecule
Proteins (2 molecules)
1
Cyclin-dependent Kinase 2
(Gene symbol: CDK2)
Molecule annotation
1
Cyclin-a2
(Gene symbol: CCNA2)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
3-[[5-cyano-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidin-2-yl]amino]benzenesulfonamide3-[[5-cyano-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidin-2-yl]amino]benzenesulfonamide
2
1
MONOTHIOGLYCEROLMONOTHIOGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303