4AZA: Improved eIF4E binding peptides by phage display guided design

PDB ID: 4AZADownload
MMDB ID: 101833
PDB Deposition Date: 2012/6/25
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.16  Å
Source Organism:
Similar Structures:
Biological Unit for 4AZA: dimeric; determined by author and by software (PISA)
Molecular Components in 4AZA
Label Count Molecule
Proteins (2 molecules)
1
Eukaryotic Translation Initiation Factor 4E
(Gene symbol: EIF4E)
Molecule annotation
1
Eif4g1_d5s Peptide
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
[[(2R,3S,4R,5R)-5-(6-AMINO-3-METHYL-4-OXO-5H-IMIDAZO[4,5-C]PYRIDIN-1-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHOXY-HYDROXY-PHOSPHORYL] PHOSPHONO HYDROGEN PHOSPHATE[[(2R,3S,4R,5R)-5-(6-AMINO-3-METHYL-4-OXO-5H-IMIDAZO[4,5-C]PYRIDIN-1-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHOXY-HYDROXY-PHOSPHORYL] PHOSPHONO HYDROGEN PHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303