4AOT: Crystal Structure of Human Serine Threonine Kinase-10 (LOK) Bound to GW830263A

PDB ID: 4AOTDownload
MMDB ID: 98725
PDB Deposition Date: 2012/3/29
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.33  Å
Source Organism:
Similar Structures:
Biological Unit for 4AOT: monomeric; determined by author and by software (PISA)
Molecular Components in 4AOT
Label Count Molecule
Protein (1 molecule)
1
Serine/threonine-protein Kinase 10
(Gene symbol: STK10)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
4
CHLORIDE IONCHLORIDE ION
2
1
1-(4-{methyl[2-({4-[(methylsulfonyl)methyl]phenyl}amino)pyrimidin-4-yl]amino}phenyl)-3-{3-[(4-methylpiperazin-1-yl)carbonyl]phenyl}urea1-(4-{methyl[2-({4-[(methylsulfonyl)methyl]phenyl}amino)pyrimidin-4-yl]amino}phenyl)-3-{3-[(4-methylpiperazin-1-yl)carbonyl]phenyl}urea
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303