4AIC: X-ray structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXR, Rv2870c, from Mycobacterium tuberculosis, in complex with fosmidomycin, manganese and NADPH

PDB ID: 4AICDownload
MMDB ID: 97501
PDB Deposition Date: 2012/2/9
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.05  Å
Source Organism:
Similar Structures:
Biological Unit for 4AIC: dimeric; determined by author and by software (PISA)
Molecular Components in 4AIC
Label Count Molecule
Proteins (2 molecules)
2
1-deoxy-d-xylulose 5-phosphate Reductoisomerase
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
1
3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID
2
2
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
3
2
MANGANESE (II) IONMANGANESE (II) ION
4
2
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303