4AF2: C61s Mutant Of Thiol Peroxidase Form E. Coli

Thiol peroxidase (Tpx) is an atypical 2-Cys peroxiredoxin, which has been suggested to be important for cell survival and virulence in Gram-negative pathogens. The structure of a catalytically inactive version of this protein in an orthorhombic crystal form has been determined by molecular replacement. Structural alignments revealed that Tpx is conserved. Analysis of the crystal packing shows that the linker region of the affinity tag is important for formation of the crystal lattice.
PDB ID: 4AF2Download
MMDB ID: 99222
PDB Deposition Date: 2012/1/16
Updated in MMDB: 2012/07
Experimental Method:
x-ray diffraction
Resolution: 1.97  Å
Source Organism:
Similar Structures:
Biological Unit for 4AF2: dimeric; determined by software (PISA)
Molecular Components in 4AF2
Label Count Molecule
Proteins (2 molecules)
Thiol Peroxidase(Gene symbol: tpx)
Molecule annotation
* Click molecule labels to explore molecular sequence information.

Citing MMDB