National Center for
4A46: Crosstalk Between Cu(i) And Zn(ii) Homeostasis
Chem. Commun. (Camb. ) (2013) 49 p.8000-8002
The copper metallochaperone Atx1 and the N-terminal metal-binding domain of a copper-transporting ATP-ase can form tight Zn(II)-mediated hetero-complexes in both cyanobacteria and humans. Copper and zinc homeostasis could be linked by metal binding to these CXXC-containing proteins.