4A2J: PR X-Ray structures in agonist conformations reveal two different mechanisms for partial agonism in 11beta-substituted steroids

PDB ID: 4A2JDownload
MMDB ID: 98555
PDB Deposition Date: 2011/9/27
Updated in MMDB: 2012/07
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 4A2J: monomeric; determined by author and by software (PISA)
Molecular Components in 4A2J
Label Count Molecule
Protein (1 molecule)
1
Progesterone Receptor
(Gene symbol: PGR)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
4-[(11BETA,17BETA)-17-METHOXY-17-(METHOXYMETHYL)-3-OXOESTRA-4,9-DIEN-11-YL]BENZALDEHYDE OXIME4-[(11BETA,17BETA)-17-METHOXY-17-(METHOXYMETHYL)-3-OXOESTRA-4,9-DIEN-11-YL]BENZALDEHYDE OXIME
2
1
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303