3ZXV: Crystal structure of Mycobacterium Tuberculosis Glutamine Synthetase in complex with tri-substituted imidazole inhibitor (4-(2-tert-butyl- 4-(6-methoxynaphthalen-2-yl)-1H-imidazol-5-yl)pyridin-2-amine) and L- methionine-S-sulfoximine phosphate

PDB ID: 3ZXVDownload
MMDB ID: 98553
PDB Deposition Date: 2011/8/16
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.26  Å
Source Organism:
Similar Structures:
Biological Unit for 3ZXV: dodecameric; determined by author and by software (PISA)
Molecular Components in 3ZXV
Label Count Molecule
Proteins (12 molecules)
12
Glutamine Synthetase 1
Molecule annotation
Chemicals and Non-standard biopolymers (84 molecules)
1
12
4-(2-TERT-BUTYL-4-(6-METHOXYNAPHTHALEN-2-YL)-3H-IMIDAZOL-4-YL)PYRIDIN-2-AMINE4-(2-TERT-BUTYL-4-(6-METHOXYNAPHTHALEN-2-YL)-3H-IMIDAZOL-4-YL)PYRIDIN-2-AMINE
2
36
MAGNESIUM IONMAGNESIUM ION
3
12
L-METHIONINE-S-SULFOXIMINE PHOSPHATEL-METHIONINE-S-SULFOXIMINE PHOSPHATE
4
12
PHOSPHATE IONPHOSPHATE ION
5
12
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303