3ZXR: Crystal structure of Mycobacterium Tuberculosis Glutamine Synthetase in complex with tri-substituted imidazole inhibitor (3-(2-tert-butyl- 5-(pyridin-4-yl)-1H-imidazol-4-yl)quinoline) and L-methionine-S- sulfoximine phosphate

PDB ID: 3ZXRDownload
MMDB ID: 98552
PDB Deposition Date: 2011/8/15
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.15  Å
Source Organism:
Similar Structures:
Biological Unit for 3ZXR: dodecameric; determined by author and by software (PISA)
Molecular Components in 3ZXR
Label Count Molecule
Proteins (12 molecules)
12
Glutamine Synthetase 1
Molecule annotation
Chemicals and Non-standard biopolymers (84 molecules)
1
12
3-(2-TERT-BUTYL-5-(PYRIDIN-4-YL)-1H-IMIDAZOL-4-YL)QUINOLINE3-(2-TERT-BUTYL-5-(PYRIDIN-4-YL)-1H-IMIDAZOL-4-YL)QUINOLINE
2
36
MAGNESIUM IONMAGNESIUM ION
3
12
L-METHIONINE-S-SULFOXIMINE PHOSPHATEL-METHIONINE-S-SULFOXIMINE PHOSPHATE
4
12
PHOSPHATE IONPHOSPHATE ION
5
12
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303