3ZRM: Identification of 2-(4-pyridyl)thienopyridinones as GSK-3beta inhibitors

PDB ID: 3ZRMDownload
MMDB ID: 92074
PDB Deposition Date: 2011/6/17
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.49  Å
Source Organism:
Similar Structures:
Biological Unit for 3ZRM: tetrameric; determined by author and by software (PISA)
Molecular Components in 3ZRM
Label Count Molecule
Proteins (4 molecules)
2
Glycogen Synthase Kinase-3 Beta
(Gene symbol: GSK3B)
Molecule annotation
2
Proto-oncogene Frat1
(Gene symbol: FRAT1)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
6
SULFATE IONSULFATE ION
2
2
GLYCEROLGLYCEROL
3
2
7-(4-HYDROXYPHENYL)-2-PYRIDIN-4-YL-5H-THIENO[3,2-C]PYRIDIN-4-ONE7-(4-HYDROXYPHENYL)-2-PYRIDIN-4-YL-5H-THIENO[3,2-C]PYRIDIN-4-ONE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303