3WZK: CRYSTAL STRUCTURE OF HUMAN MPS1 CATALYTIC DOMAIN IN COMPLEX WITH N-cyclopropyl-4-(8-((thiophen-2-ylmethyl)amino)imidazo[1,2-a]pyrazin-3-yl)benzamide

PDB ID: 3WZKDownload
MMDB ID: 126811
PDB Deposition Date: 2014/9/29
Updated in MMDB: 2022/08
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 3WZK: monomeric; determined by author
Molecular Components in 3WZK
Label Count Molecule
Protein (1 molecule)
1
Dual Specificity Protein Kinase TTK
(Gene symbol: TTK)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
CHLORIDE IONCHLORIDE ION
2
1
N-cyclopropyl-4-{8-[(thiophen-2-ylmethyl)amino]imidazo[1,2-a]pyrazin-3-yl}benzamideN-cyclopropyl-4-{8-[(thiophen-2-ylmethyl)amino]imidazo[1,2-a]pyrazin-3-yl}benzamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303