3WZE: KDR in complex with ligand sorafenib

PDB ID: 3WZEDownload
MMDB ID: 129547
PDB Deposition Date: 2014/9/24
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 3WZE: monomeric; determined by author and by software (PISA)
Molecular Components in 3WZE
Label Count Molecule
Protein (1 molecule)
1
Vascular Endothelial Growth Factor Receptor 2
(Gene symbol: KDR)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE
2
1
ACETATE IONACETATE ION
3
1
2,3-DIHYDROXY-1,4-DITHIOBUTANE2,3-DIHYDROXY-1,4-DITHIOBUTANE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303