3WYX: CRYSTAL STRUCTURE OF HUMAN MPS1 CATALYTIC DOMAIN IN COMPLEX WITH 6-((3-(cyanomethoxy)-4-(1-methyl-1H-pyrazol-4-yl)phenyl)amino)-2-(cyclohexylamino)nicotinonitrile

PDB ID: 3WYXDownload
MMDB ID: 128339
PDB Deposition Date: 2014/9/9
Updated in MMDB: 2022/08
Experimental Method:
x-ray diffraction
Resolution: 2.9  Å
Source Organism:
Similar Structures:
Biological Unit for 3WYX: monomeric; determined by author
Molecular Components in 3WYX
Label Count Molecule
Protein (1 molecule)
1
Dual Specificity Protein Kinase TTK
(Gene symbol: TTK)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
IODIDE ION (Link to PubChem not yet available)IODIDE ION
2
1
6-{[3-(cyanomethoxy)-4-(1-methyl-1H-pyrazol-4-yl)phenyl]amino}-2-(cyclohexylamino)pyridine-3-carbonitrile (Link to PubChem not yet available)6-{[3-(cyanomethoxy)-4-(1-methyl-1H-pyrazol-4-yl)phenyl]amino}-2-(cyclohexylamino)pyridine-3-carbonitrile
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303