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3WYX:
CRYSTAL STRUCTURE OF HUMAN MPS1 CATALYTIC DOMAIN IN COMPLEX WITH 6-((3-(cyanomethoxy)-4-(1-methyl-1H-pyrazol-4-yl)phenyl)amino)-2-(cyclohexylamino)nicotinonitrile
PDB ID:
3WYX
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MMDB ID:
128339
PDB Deposition Date:
2014/9/9
Updated in MMDB:
2022/08
Experimental Method:
x-ray diffraction
Resolution:
2.9 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 3WYX: monomeric; determined by author
Molecular Components in 3WYX
Label
Count
Molecule
Protein (1 molecule)
A
1
Dual Specificity Protein Kinase TTK
(Gene symbol:
TTK
)
Chemicals and Non-standard biopolymers (2 molecules)
1
1
IODIDE ION
2
1
6-{[3-(cyanomethoxy)-4-(1-methyl-1H-pyrazol-4-yl)phenyl]amino}-2-(cyclohexylamino)pyridine-3-carbonitrile
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303