3UVX: Crystal Structure of the first bromodomain of human BRD4 in complex with a diacetylated histone 4 peptide (H4K12acK16ac)

PDB ID: 3UVXDownload
MMDB ID: 96770
PDB Deposition Date: 2011/11/30
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.91  Å
Source Organism:
Similar Structures:
Biological Unit for 3UVX: dimeric; determined by author and by software (PISA)
Molecular Components in 3UVX
Label Count Molecule
Proteins (2 molecules)
1
Bromodomain-containing Protein 4
(Gene symbol: BRD4)
Molecule annotation
1
Diacetylated Histone 4 Peptide
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
SODIUM IONSODIUM ION
2
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
3
FORMIC ACIDFORMIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303