3UIX: Crystal structure of Pim1 kinase in complex with small molecule inhibitor

PDB ID: 3UIXDownload
MMDB ID: 98684
PDB Deposition Date: 2011/11/6
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 3UIX: monomeric; determined by author and by software (PISA)
Molecular Components in 3UIX
Label Count Molecule
Protein (1 molecule)
1
Proto-oncogene Serine/threonine-protein Kinase Pim-1
(Gene symbol: PIM1)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
2-{4-[(3-aminopropyl)amino]quinazolin-2-yl}phenol2-{4-[(3-aminopropyl)amino]quinazolin-2-yl}phenol
2
2
CHLORIDE IONCHLORIDE ION
3
1
SULFATE IONSULFATE ION
4
1
CALCIUM IONCALCIUM ION
5
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303