3U78: E67-2 selectively inhibits KIAA1718, a human histone H3 lysine 9 Jumonji demethylase

PDB ID: 3U78Download
MMDB ID: 96728
PDB Deposition Date: 2011/10/13
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2.689  Å
Source Organism:
Similar Structures:
Biological Unit for 3U78: monomeric; determined by author
Molecular Components in 3U78
Label Count Molecule
Protein (1 molecule)
1
Lysine-specific Demethylase 7
(Gene symbol: KDM7A)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
1
2-OXOGLUTARIC ACID2-OXOGLUTARIC ACID
2
1
NICKEL (II) IONNICKEL (II) ION
3
1
CHLORIDE IONCHLORIDE ION
4
1
SULFATE IONSULFATE ION
5
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
6
1
7-[(5-aminopentyl)oxy]-N~4~-(1-benzylpiperidin-4-yl)-N~2~-[3-(dimethylamino)propyl]-6-methoxyquinazoline-2,4-diamine7-[(5-aminopentyl)oxy]-N~4~-(1-benzylpiperidin-4-yl)-N~2~-[3-(dimethylamino)propyl]-6-methoxyquinazoline-2,4-diamine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303