3TU1: Exhaustive Fluorine Scanning towards Potent p53-MDM2 Antagonist

PDB ID: 3TU1Download
MMDB ID: 94828
PDB Deposition Date: 2011/9/15
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 1.603  Å
Source Organism:
Similar Structures:
Biological Unit for 3TU1: monomeric; determined by author and by software (PISA)
Molecular Components in 3TU1
Label Count Molecule
Protein (1 molecule)
1
E3 Ubiquitin-protein Ligase Mdm2
(Gene symbol: MDM2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
3-[(1S)-2-(tert-butylamino)-1-{N-[(3,4-difluorophenyl)methyl]formamido}-2-oxoethyl]-6-chloro-1H-indole-2-carboxylic acid3-[(1S)-2-(tert-butylamino)-1-{N-[(3,4-difluorophenyl)methyl]formamido}-2-oxoethyl]-6-chloro-1H-indole-2-carboxylic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303