3TPX: Crystal structure of human MDM2 in complex with a trifluoromethylated D-peptide inhibitor

PDB ID: 3TPXDownload
MMDB ID: 100662
PDB Deposition Date: 2011/9/8
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 3TPX: trimeric; determined by author and by software (PISA)
Molecular Components in 3TPX
Label Count Molecule
Protein (1 molecule)
1
E3 Ubiquitin-protein Ligase Mdm2
(Gene symbol: MDM2)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
BD
2
D-peptide inhibitor DPMI-delta
1
2
SULFATE IONSULFATE ION
2
1
CHLORIDE IONCHLORIDE ION
3
1
ACETATE IONACETATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303