3TBG: Human cytochrome P450 2D6 with two thioridazines bound in active site

PDB ID: 3TBGDownload
MMDB ID: 101766
PDB Deposition Date: 2011/8/5
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 3TBG: monomeric; determined by author
Molecular Components in 3TBG
Label Count Molecule
Protein (1 molecule)
1
Cytochrome P450 2D6
(Gene symbol: CYP2D6)
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
2
10-{2-[(2R)-1-methylpiperidin-2-yl]ethyl}-2-(methylsulfanyl)-10H-phenothiazine10-{2-[(2R)-1-methylpiperidin-2-yl]ethyl}-2-(methylsulfanyl)-10H-phenothiazine
2
3
ZINC IONZINC ION
3
4
GLYCEROLGLYCEROL
4
1
PHOSPHATE IONPHOSPHATE ION
5
1
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303