3T9T: Crystal structure of BTK mutant (F435T,K596R) complexed with Imidazo[1,5-a]quinoxaline

PDB ID: 3T9TDownload
MMDB ID: 94287
PDB Deposition Date: 2011/8/3
Updated in MMDB: 2011/10
Experimental Method:
x-ray diffraction
Resolution: 1.65  Å
Source Organism:
Similar Structures:
Biological Unit for 3T9T: monomeric; determined by author and by software (PISA)
Molecular Components in 3T9T
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Kinase Itk/tsk
(Gene symbol: ITK)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
(2Z)-4-(dimethylamino)-N-{7-fluoro-4-[(2-methylphenyl)amino]imidazo[1,5-a]quinoxalin-8-yl}-N-methylbut-2-enamide(2Z)-4-(dimethylamino)-N-{7-fluoro-4-[(2-methylphenyl)amino]imidazo[1,5-a]quinoxalin-8-yl}-N-methylbut-2-enamide
2
2
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303