3T4R: Lettuce Necrotic Yellow Virus Phosphoprotein C-terminal Domain

Citation:
Abstract
Lettuce necrotic yellows virus (LNYV) is a prototype of the plant-adapted cytorhabdoviruses. Through a meta-prediction of disorder, we localized a folded C-terminal domain in the amino acid sequence of its phosphoprotein. This domain consists of an autonomous folding unit that is monomeric in solution. Its structure, solved by X-ray crystallography, reveals a lollipop-shaped structure comprising five helices. The structure is different from that of the corresponding domains of other Rhabdoviridae, Filoviridae, and Paramyxovirinae; only the overall topology of the polypeptide chain seems to be conserved, suggesting that this domain evolved under weak selective pressure and varied in size by the acquisition or loss of functional modules.
PDB ID: 3T4RDownload
MMDB ID: 107090
PDB Deposition Date: 2011/7/26
Updated in MMDB: 2014/03
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 3T4R: monomeric; determined by author
Molecular Components in 3T4R
Label Count Molecule
Protein (1 molecule)
1
Phosphoprotein(Gene symbol: P)
Molecule annotation
Chemical (1 molecule)
1
1
* Click molecule labels to explore molecular sequence information.

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