3T03: Crystal structure of PPAR gamma ligand binding domain in complex with a novel partial agonist GQ-16

PDB ID: 3T03Download
MMDB ID: 99836
PDB Deposition Date: 2011/7/19
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 3T03: dimeric; determined by author and by software (PISA)
Molecular Components in 3T03
Label Count Molecule
Proteins (2 molecules)
1
Peroxisome Proliferator-activated Receptor Gamma
(Gene symbol: PPARG)
Molecule annotation
1
Nuclear Receptor Coactivator 1
(Gene symbol: NCOA1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(5Z)-5-(5-bromo-2-methoxybenzylidene)-3-(4-methylbenzyl)-1,3-thiazolidine-2,4-dione(5Z)-5-(5-bromo-2-methoxybenzylidene)-3-(4-methylbenzyl)-1,3-thiazolidine-2,4-dione
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303