3SVI: Structure of the Pto-binding domain of HopPmaL generated by limited thermolysin digestion

Citation:
Abstract
HopPmaL is a member of the HopAB family of type III effectors present in the phytopathogen Pseudomonas syringae. Using both X-ray crystallography and solution nuclear magnetic resonance, we demonstrate that HopPmaL contains two structurally homologous yet functionally distinct domains. The N-terminal domain corresponds to the previously described Pto-binding domain, while the previously uncharacterised C-terminal domain spans residues 308-385. While structurally similar, these domains do not share significant sequence similarity and most importantly demonstrate significant differences in key residues involved in host protein recognition, suggesting that each of them targets a different host protein.
PDB ID: 3SVIDownload
MMDB ID: 92633
PDB Deposition Date: 2011/7/12
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 3SVI: monomeric; determined by author
Molecular Components in 3SVI
Label Count Molecule
Protein (1 molecule)
1
Type III Effector Hopab2
Molecule annotation
Chemicals (7 molecules)
1
2
2
1
3
4
* Click molecule labels to explore molecular sequence information.

Citing MMDB
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