3SI8: Human DNA polymerase eta - DNA ternary complex with the 5'T of a CPD in the active site (TT2)

PDB ID: 3SI8Download
MMDB ID: 92387
PDB Deposition Date: 2011/6/17
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2.15  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 3SI8: trimeric; determined by author and by software (PISA)
Molecular Components in 3SI8
Label Count Molecule
Protein (1 molecule)
1
DNA Polymerase ETA
Molecule annotation
Nucleotides(2 molecules)
1
DNA (5'-d(*tp*a*ap*cp*(ttd)p*ap*tp*gp*ap*cp*gp*c)-3')
Molecule annotation
1
DNA (5'-d(*tp*gp*cp*gp*tp*cp*ap*tp*a)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (20 molecules)
1
1
2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine
2
8
GLYCEROLGLYCEROL
3
1
(2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol(2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol
4
2
2,3-DIHYDROXY-1,4-DITHIOBUTANE2,3-DIHYDROXY-1,4-DITHIOBUTANE
5
5
1,2-ETHANEDIOL1,2-ETHANEDIOL
6
2
MAGNESIUM IONMAGNESIUM ION
7
1
COBALT (II) IONCOBALT (II) ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303