3SH2: Staphylococcus aureus Dihydrofolate Reductase complexed with NADPH and 6-ethyl-5-(3-(4-methoxybiphenyl-3-yl)prop-1-ynyl)pyrimidine-2,4-diamine (UCP120J)

PDB ID: 3SH2Download
MMDB ID: 97759
PDB Deposition Date: 2011/6/15
Updated in MMDB: 2013/11
Experimental Method:
x-ray diffraction
Resolution: 2.999  Å
Source Organism:
Similar Structures:
Biological Unit for 3SH2: monomeric; determined by author and by software (PISA)
Molecular Components in 3SH2
Label Count Molecule
Protein (1 molecule)
1
Dihydrofolate Reductase
(Gene symbol: dfrA)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
1
6-ethyl-5-[3-(4-methoxybiphenyl-3-yl)prop-1-yn-1-yl]pyrimidine-2,4-diamine6-ethyl-5-[3-(4-methoxybiphenyl-3-yl)prop-1-yn-1-yl]pyrimidine-2,4-diamine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303