3SFY: Cryptococcus neoformans protein farnesyltransferase in complex with FPT-II and ethylenediamine inhibitor 2

PDB ID: 3SFYDownload
MMDB ID: 92384
PDB Deposition Date: 2011/6/14
Updated in MMDB: 2011/10
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 3SFY: dimeric; determined by author and by software (PISA)
Molecular Components in 3SFY
Label Count Molecule
Proteins (2 molecules)
1
Cryptococcus Neoformans Protein Farnesyltransferase Alpha Subunit
Molecule annotation
1
Cryptococcus Neoformans Protein Farnesyltransferase Beta Subunit
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
1
ZINC IONZINC ION
2
3
(2R)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid(2R)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid
3
1
N-(2-{(4-bromophenyl)[(1-methyl-1H-imidazol-5-yl)methyl]amino}ethyl)-1-methyl-N-(2-methylbenzyl)-1H-imidazole-4-sulfonamideN-(2-{(4-bromophenyl)[(1-methyl-1H-imidazol-5-yl)methyl]amino}ethyl)-1-methyl-N-(2-methylbenzyl)-1H-imidazole-4-sulfonamide
4
1
[(3,7,11-TRIMETHYL-DODECA-2,6,10-TRIENYLOXYCARBAMOYL)-METHYL]-PHOSPHONIC ACID[(3,7,11-TRIMETHYL-DODECA-2,6,10-TRIENYLOXYCARBAMOYL)-METHYL]-PHOSPHONIC ACID
5
1
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303