3RTH: Structure of Bace-1 (Beta-Secretase) in Complex with 6-(2-(3,3-Dimethylbut-1-ynyl)phenyl)quinolin-2-amine

PDB ID: 3RTHDownload
MMDB ID: 93310
PDB Deposition Date: 2011/5/3
Updated in MMDB: 2024/11
Experimental Method:
x-ray diffraction
Resolution: 2.7  Å
Source Organism:
Similar Structures:
Biological Unit for 3RTH: monomeric; determined by author and by software (PISA)
Molecular Components in 3RTH
Label Count Molecule
Protein (1 molecule)
1
Beta-secretase 1
(Gene symbol: BACE1)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
4
IODIDE IONIODIDE ION
2
1
6-[2-(3,3-dimethylbut-1-yn-1-yl)phenyl]quinolin-2-amine6-[2-(3,3-dimethylbut-1-yn-1-yl)phenyl]quinolin-2-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303