3RCD: HER2 Kinase Domain Complexed with TAK-285

PDB ID: 3RCDDownload
MMDB ID: 95214
PDB Deposition Date: 2011/3/30
Updated in MMDB: 2011/12
Experimental Method:
x-ray diffraction
Resolution: 3.21  Å
Source Organism:
Similar Structures:
Biological Unit for 3RCD: monomeric; determined by author
Molecular Components in 3RCD
Label Count Molecule
Protein (1 molecule)
1
Receptor Tyrosine-protein Kinase Erbb-2
(Gene symbol: ERBB2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-{2-[4-({3-chloro-4-[3-(trifluoromethyl)phenoxy]phenyl}amino)-5H-pyrrolo[3,2-d]pyrimidin-5-yl]ethyl}-3-hydroxy-3-methylbutanamideN-{2-[4-({3-chloro-4-[3-(trifluoromethyl)phenoxy]phenyl}amino)-5H-pyrrolo[3,2-d]pyrimidin-5-yl]ethyl}-3-hydroxy-3-methylbutanamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303