3R7X: Crystal Structure Analysis Of A Quinazolinedione Sulfonamide Bound To Human Glur2: A Novel Class Of Competitive Ampa Receptor Antagonists With Oral Activity

PDB ID: 3R7XDownload
MMDB ID: 90654
PDB Deposition Date: 2011/3/23
Updated in MMDB: 2017/07
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 3R7X: dimeric; determined by author and by software (PISA)
Molecular Components in 3R7X
Label Count Molecule
Proteins (2 molecules)
2
Glutamate Receptor 2
(Gene symbol: GRIA2)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
N-[6-(1h-Imidazol-1-Yl)-7-Nitro-2,4-Dioxo-1,4-Dihydroquinazolin-3(2h)-Yl]methanesulfonamideN-[6-(1h-Imidazol-1-Yl)-7-Nitro-2,4-Dioxo-1,4-Dihydroquinazolin-3(2h)-Yl]methanesulfonamide
2
1
Glutamic AcidGlutamic Acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303