3R4B: Crystal Structure of Wild-type HIV-1 Protease in Complex With TMC310911

PDB ID: 3R4BDownload
MMDB ID: 93709
PDB Deposition Date: 2011/3/17
Updated in MMDB: 2011/12
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 3R4B: dimeric; determined by author and by software (PISA)
Molecular Components in 3R4B
Label Count Molecule
Proteins (2 molecules)
2
Hiv-1 Protease
(Gene symbol: gag-pol)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-4-[({2-[(1-cyclopentylpiperidin-4-yl)amino]-1,3-benzothiazol-6-yl}sulfonyl)(2-methylpropyl)amino]-3-hydroxy-1-p henylbutan-2-yl}carbamate(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-4-[({2-[(1-cyclopentylpiperidin-4-yl)amino]-1,3-benzothiazol-6-yl}sulfonyl)(2-methylpropyl)amino]-3-hydroxy-1-p henylbutan-2-yl}carbamate
2
1
PHOSPHATE IONPHOSPHATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303