3R02: The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors

PDB ID: 3R02Download
MMDB ID: 90488
PDB Deposition Date: 2011/3/7
Updated in MMDB: 2011/05
Experimental Method:
x-ray diffraction
Resolution: 1.95  Å
Source Organism:
Similar Structures:
Biological Unit for 3R02: monomeric; determined by author and by software (PISA)
Molecular Components in 3R02
Label Count Molecule
Protein (1 molecule)
1
Proto-oncogene Serine/threonine-protein Kinase Pim-1
(Gene symbol: PIM1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
7-[(cis-4-aminocyclohexyl)amino]-5-bromo-1-benzofuran-2-carboxylic acid7-[(cis-4-aminocyclohexyl)amino]-5-bromo-1-benzofuran-2-carboxylic acid
2
3
IMIDAZOLEIMIDAZOLE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303