3QYL: Sensitivity of receptor internal motions to ligand binding affinity and kinetic off-rate

PDB ID: 3QYLDownload
MMDB ID: 96507
PDB Deposition Date: 2011/3/3
Updated in MMDB: 2014/11
Experimental Method:
x-ray diffraction
Resolution: 1.79  Å
Source Organism:
Similar Structures:
Biological Unit for 3QYL: monomeric; determined by author and by software (PISA)
Molecular Components in 3QYL
Label Count Molecule
Protein (1 molecule)
1
Dihydrofolate Reductase
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
(7S)-7-methyl-5,6,7,8-tetrahydroquinazoline-2,4-diamine(7S)-7-methyl-5,6,7,8-tetrahydroquinazoline-2,4-diamine
2
1
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
3
2
CALCIUM IONCALCIUM ION
4
1
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303