3QVI: Crystal Structure Of Kni-10395 Bound Histo-Aspartic Protease (Hap) From Plasmodium Falciparum

PDB ID: 3QVIDownload
MMDB ID: 94242
PDB Deposition Date: 2011/2/25
Updated in MMDB: 2011/12
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 3QVI: tetrameric; determined by author
Molecular Components in 3QVI
Label Count Molecule
Proteins (4 molecules)
4
Histo-aspartic Protease
(Gene symbol: PF3D7_1408100)
Molecule annotation
Chemicals and Non-standard biopolymers (22 molecules)
1
3
(4r)-n-[(1s,2r)-2-hydroxy-2,3-dihydro-1h-inden-1-yl]-3-[(2s,3s)-2-hydroxy-3-{[s-methyl-n-(phenylacetyl)-l-cysteinyl]amino}-4-phenylbutanoyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxamideKni-10395
2
12
1,2-ethanediolEthylene Glycol
3
4
Tetraethylene GlycolTetraethylene Glycol
4
1
Acetate IonAcetate Ion
5
1
1-methoxy-2-[2-(2-methoxy-ethoxy]-ethane1-methoxy-2-[2-(2-methoxy-ethoxy]-ethane
6
1
Sodium IonSodium Ion
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303