3QI2: A Galpha P-loop mutation prevents transition to the activated state: G42R bound to RGS14 GoLoco

PDB ID: 3QI2Download
MMDB ID: 96880
PDB Deposition Date: 2011/1/26
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2.797  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 3QI2: dimeric; determined by author and by software (PISA)
Molecular Components in 3QI2
Label Count Molecule
Proteins (2 molecules)
1
Guanine Nucleotide-binding Protein G(i) Subunit Alpha-1
Molecule annotation
1
Regulator of G-protein Signaling 14
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
GUANOSINE-5'-DIPHOSPHATEGUANOSINE-5'-DIPHOSPHATE
2
1
SULFATE IONSULFATE ION
3
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303