3QF9: Crystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and a furan-thiazolidinedione ligand

PDB ID: 3QF9Download
MMDB ID: 88990
PDB Deposition Date: 2011/1/21
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 3QF9: dimeric; determined by author and by software (PISA)
Molecular Components in 3QF9
Label Count Molecule
Proteins (2 molecules)
1
Proto-oncogene Serine/threonine-protein Kinase Pim-1
Molecule annotation
1
Pimtide
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
6-{5-[(Z)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]furan-2-yl}-N-{3-[(4-ethylpiperazin-1-yl)methyl]-5-(trifluoromethyl)phenyl}naphthalene-1-carboxamide6-{5-[(Z)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]furan-2-yl}-N-{3-[(4-ethylpiperazin-1-yl)methyl]-5-(trifluoromethyl)phenyl}naphthalene-1-carboxamide
2
1
SODIUM IONSODIUM ION
3
1
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303