3Q7F: Cryptococcus neoformans protein farnesyltransferase in complex with FPP and ethylenediamine inhibitor 1

PDB ID: 3Q7FDownload
MMDB ID: 92341
PDB Deposition Date: 2011/1/4
Updated in MMDB: 2011/10
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 3Q7F: dimeric; determined by author and by software (PISA)
Molecular Components in 3Q7F
Label Count Molecule
Proteins (2 molecules)
1
Farnesyltransferase Alpha Subunit
Molecule annotation
1
Farnesyltransferase Beta Subunit
Molecule annotation
Chemicals and Non-standard biopolymers (13 molecules)
1
3
alpha-D-glucopyranosealpha-D-glucopyranose
2
3
beta-D-fructofuranosebeta-D-fructofuranose
3
1
ZINC IONZINC ION
4
3
(2S)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid(2S)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid
5
1
FARNESYL DIPHOSPHATEFARNESYL DIPHOSPHATE
6
1
SULFATE IONSULFATE ION
7
1
N-benzyl-N-(2-{(4-cyanophenyl)[(1-methyl-1H-imidazol-5-yl)methyl]amino}ethyl)-1-methyl-1H-imidazole-4-sulfonamideN-benzyl-N-(2-{(4-cyanophenyl)[(1-methyl-1H-imidazol-5-yl)methyl]amino}ethyl)-1-methyl-1H-imidazole-4-sulfonamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303