3Q7A: Cryptococcus neoformans protein farnesyltransferase in complex with FPP and L-778,123

PDB ID: 3Q7ADownload
MMDB ID: 92340
PDB Deposition Date: 2011/1/4
Updated in MMDB: 2012/12
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 3Q7A: dimeric; determined by author and by software (PISA)
Molecular Components in 3Q7A
Label Count Molecule
Proteins (2 molecules)
1
Farnesyltransferase Alpha Subunit
Molecule annotation
1
Farnesyltransferase Beta Subunit
Molecule annotation
Chemicals and Non-standard biopolymers (13 molecules)
1
3
alpha-D-glucopyranosealpha-D-glucopyranose
2
3
beta-D-fructofuranosebeta-D-fructofuranose
3
1
ZINC IONZINC ION
4
3
(2R)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid(2R)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid
5
1
SULFATE IONSULFATE ION
6
1
FARNESYL DIPHOSPHATEFARNESYL DIPHOSPHATE
7
1
4-[(5-{[4-(3-CHLOROPHENYL)-3-OXOPIPERAZIN-1-YL]METHYL}-1H-IMIDAZOL-1-YL)METHYL]BENZONITRILE4-[(5-{[4-(3-CHLOROPHENYL)-3-OXOPIPERAZIN-1-YL]METHYL}-1H-IMIDAZOL-1-YL)METHYL]BENZONITRILE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303