3PZ2: Crystal structure of RabGGTase(DELTA LRR; DELTA IG) in Complex with BMS3 and lipid substrate GGPP

PDB ID: 3PZ2Download
MMDB ID: 90458
PDB Deposition Date: 2010/12/14
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2.35  Å
Source Organism:
Similar Structures:
Biological Unit for 3PZ2: dimeric; determined by author and by software (PISA)
Molecular Components in 3PZ2
Label Count Molecule
Proteins (2 molecules)
1
Geranylgeranyl Transferase Type-2 Subunit Alpha
(Gene symbol: Rabggta)
Molecule annotation
1
Geranylgeranyl Transferase Type-2 Subunit Beta
(Gene symbol: Rabggtb)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
ZINC IONZINC ION
2
1
CALCIUM IONCALCIUM ION
3
1
(3R)-3-benzyl-4-[(4-methoxyphenyl)sulfonyl]-1-[(1-methyl-1H-imidazol-5-yl)methyl]-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine-7-carbonitrile(3R)-3-benzyl-4-[(4-methoxyphenyl)sulfonyl]-1-[(1-methyl-1H-imidazol-5-yl)methyl]-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine-7-carbonitrile
4
1
GERANYLGERANYL DIPHOSPHATEGERANYLGERANYL DIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303