3PVU: Bovine GRK2 in complex with Gbetagamma subunits and a selective kinase inhibitor (CMPD101)

PDB ID: 3PVUDownload
MMDB ID: 90987
PDB Deposition Date: 2010/12/7
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2.48  Å
Source Organism:
Similar Structures:
Biological Unit for 3PVU: trimeric; determined by author and by software (PISA)
Molecular Components in 3PVU
Label Count Molecule
Proteins (3 molecules)
1
Beta-adrenergic Receptor Kinase 1
(Gene symbol: GRK2)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
(Gene symbol: GNB1)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
(Gene symbol: GNG2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
3-({[4-methyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]methyl}amino)-N-[2-(trifluoromethyl)benzyl]benzamide3-({[4-methyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]methyl}amino)-N-[2-(trifluoromethyl)benzyl]benzamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303